CD8 alpha Antikörper (violetFluor™ 450)

Produktnummer ABIN2567972

Dieses Ratte Monoklonal-Antikörper erkennt spezifisch CD8 alpha in FACS. Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für CD8 alpha Antikörper (violetFluor™ 450) (ABIN2567972)

Target: CD8 alpha (CD8A) (CD8a Molecule (CD8A))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser CD8 alpha Antikörper ist konjugiert mit violetFluor™ 450

Applikation: Flow Cytometry (FACS)

Klon: 2-43

Produktdetails anti-CD8 alpha Antikörper (violetFluor™ 450)

Spezifität: The 2.43 monoclonal antibody specifically reacts with mouse CD8 antigen.

Aufreinigung: The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Lagerung: 4 °C

Informationen zur Lagerung: The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.

Details zu CD8 alpha

Target: CD8 alpha (CD8A) (CD8a Molecule (CD8A))

Andere Bezeichnung: CD8a

Hintergrund: The 2.43 monoclonal antibody specifically reacts with mouse CD8 antigen. CD8a (the alpha chains) form heterodimers with CD8b (the beta chains) or homodimers (alpha-alpha), which occur as receptors on the surface of the majority of thymocytes. A subpopulation of mature T lymphocytes expresses the CD8 alpha beta (alpha beta TCR T cells), and a subpopulation of intestinal intraepithelial lymphocytes and dendritic cells express CD8a without CD8b. CD8 interacts with the mouse major histocompatibility complex class I (MHC class I) molecules on antigen-presenting cells or epithelial cells. BG Violet 450 conjugate is an alternative to the Pacific Blue, eFluor 450, or BD Horizon V450 dyes. It is excited by the violet (405 nm) laser, with a peak emission of 450nm.

Gen-ID: 12525

UniProt: P01731

Pathways: T-Zell Rezeptor Signalweg